Lymphogranuloma Venerum (Lymphogranuloma Inguinale)

Lymphogranuloma venerum or lymphogranuloma inguinale is a sexually transmitted disease caused by the bacteria Chlamydia trachomatis resulting in a painless ulcer on the genitals and swollen pelvic lymph nodes and tissues.

Where does it occur?

It occurs worldwide but is more common in tropical countries and in lower socioeconomic populations.

How is it transmitted?

It is transmitted by direct contact with lesions during sexual intercourse.

Is it contagious from person to person?


What is the risk for travelers?

The risk is high if engaged in unprotected intercourse with locals during travel in tropical countries.

How soon after exposure will one develop symptoms?

Symptoms usually develop within a month for ulcers and a few months for swelling of lymph glands and surrounding tissues.

What are the signs and symptoms?

Symptoms usually start with a painless ulcer or nodular lesion on the penis or vaginal fold; subsequently lymph glands in the groin and pelvic region swell up and may develop large ulcers. One can see some fever, chills, joint pains etc as well. Rarely complications like fistula formation, swollen joints and meningitis can occur.

Are there any lab tests to diagnose the illness?

Diagnosis is made by detecting the organism by culture, DNA probe or PCR from infected tissue.

Is there any treatment?

Antibiotics like Tetracycline, Doxycycline and Erythromycin are effective.

What preventive measures can be taken?

Avoid unprotected sex with individuals whom you do not know.

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