Malarone (Atovaquone / Proguanil)

Recommended for:

a) Prevention of chloroquine resistant malaria
b) Treatment of mild to moderate chloroquine resistant malaria

Dose:

a)   Prevention : 250 mg/100 mg tablet; one tablet, once a day, by mouth, starting 2 days prior to trip, during trip and for 7 days after return
b)  Treatment: 250 mg/100 mg tablet; 4 tablets, once a day, by mouth, for 3 consecutive days

Take with food:

Yes

Pregnancy risk:

Avoid if pregnant

Alcohol drinking:

OK

Breast Feeding Risk:

Avoid if breast feeding

Contraindications:

Allergy to atovaquone or proguanil or components of the tablet

Special precautions:

Avoid in individuals with moderate to severe kidney failure
Avoid in individuals with moderate to severe liver failure

Common Side effects:

Stomach pains, nausea and vomiting
Headache, dizziness
Itching of skin, weakness
Elevation of liver enzyme levels

Common Drug interactions:

Increases the bleeding time with warfarin (Coumadin).

Discuss above and other medication interactions with your pharmacist.

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