a) Prevention of choroquine resistant malaria
b) Treatment of chloroquine resistant malaria
a) Prevention – 250 mg tablet, once a week starting one week prior to trip, during trip and for four weeks after return.
b) Treatment – 250 mg tablet, 5 tablets all at once for mild –moderate malaria and seek medical attention.
Take with food:
Avoid if pregnant
Breast feeding risk:
Avoid if breast feeding
Allergy to mefloquine or aminoquinoline compounds (quinine/quinidine)
Heart rhythm disturbances
Psychiatric illness (depression/schizophrenia)
Common Side effects:
Nausea, vomiting, diarrhea and abdominal cramps/pains
Headache, fever, chills
Muscle pains, body aches
Ringing in the ears, dizzines
Common Drug interactions:
Vaccinations should be delayed at least 3 days prior to mefloquine.
Decreases blood levels of phenytoin, valproic acid, carbamazepine, phenobarbital.
Interaction with quinine/quinidine can result in heart rhythm abnormalities and seizures.
Discuss above and other medication interactions with your pharmacist.